Journal of Clinical Nutrition & Dietetics

The Impact of Inositol Supplementation on Menstrual Cycle Regularity and Quality of Life in Those with Polycystic Ovarian Syndrome: A Narrative Review

Approximately ten percent of patients of childbearing age are diagnosed with Polycystic Ovarian Syndrome (PCOS) in the United States, a condition that is a common cause of infertility. For some, a PCOS diagnosis may come before any plans to become pregnant. For this group of patients, addressing menstrual cycle regularity may lower anxiety related to breakthrough bleeding, add to emotional wellbeing, and improve overall quality of life. This review summarizes the quantitative research on inositol as a therapy for menstrual cycle regularity and quality of life in patients with PCOS. It also identifies implications for the therapeutic use of inositol to improve outcomes for patients with PCOS who are not actively pursuing pregnancy. As a result of the review, it can be concluded that inositol supplementation supports menstrual cycle regularity and improves quality of life in all patients diagnosed with PCOS. Additional research is needed regarding nutritional therapies for PCOS patients who wish to improve their reproductive system health outside of the context of fertility.

Author(s): Jonene Ford*

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