Journal of Clinical Nutrition & Dietetics

Association of Inorganic Phosphates Intake with (Urinary P/UUN) Ratio in CKD Patients

Chronic Kidney Disease (CKD) is a major public health concern and managing the dietary intake of phosphorus is a key aspect of treatment. As Chronic Kidney Disease (CKD) progresses, the kidneys ability to filter and excrete waste products, including phosphate, decreases. This leads to a buildup of phosphate in the blood, known as hyperphosphatemia. However, In CKD patients, a diet high in inorganic phosphates, which are commonly added to processed foods and are highly bioavailable, can contribute to hyperphosphatemia in CKD patients associated with increased morbidity and mortality. The burden of CKD on public health is substantial as it reduces the quality of life for those affected and places a significant financial burden on healthcare systems. Assessing dietary phosphorus intake and monitoring the P/UUN ratio in addition to serum phosphate levels is crucial in fully assessing phosphorus balance in CKD patients. The P/UUN ratio has the potential to be used as a predictor of hyperphosphatemia and a target for intervention in CKD patients, the literature review aims to determine the relationship between the ratio of P/UUN in urine with a diet, high in inorganic phosphates in CKD patients to gather and analyze existing research on the topic to determine the current understanding of the relationship between the two. Dietitians can use this information to guide therapy and treatment decisions, such as adjusting dietary restrictions to improve a patient’s nutritional status and slow down the progression of CKD.

Author(s): Jyotsna Puthran

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